Hypothryroidism and Weight Loss
What is the relationship between hypothyroidism and weight gain?
Since the BMR (basic metabolic rate) in the patient with hypothyroidism is decreased, an under active thyroid is generally associated
with some weight gain. The weight gain is often greater in those
individuals with more severe hypothyroidism. However, the decrease
in BMR due to hypothyroidism is usually much less dramatic than the
marked increase seen in hyperthyroidism, leading to more modest
alterations in weight due to the under active thyroid. The cause of the
weight gain in hypothyroid individuals is also complex, and not always
related to excess fat accumulation. Most of the extra weight gained in
hypothyroid individuals is due to excess accumulation of salt and water.
Massive weight gain is rarely associated with hypothyroidism. In general,
5-10 pounds of body weight may be attributable to the thyroid,
depending on the severity of the hypothyroidism. Finally, if weight gain
is the only symptom of hypothyroidism that is present, it is less likely
that the weight gain is solely due to the thyroid.
How much weight can I expect to lose once the hypothyroidism is
treated?
Since much of the weight gain in hypothyroidism is accumulation in
salt and water, when the hypothyroidism is treated one can expect a
small (usually less than 10% of body weight) weight loss. As in the
treatment with hyperthyroidism, treatment of the abnormal state of
hypothyroidism with thyroid hormone should result in a return of body
weight to what it was before the hypothyroidism developed. However,
since hypothyroidism usually develops over a long period of time, it
fairly common to find that there is no significant weight loss after
successful treatment of hypothyroidism. Again, if all of the other
symptoms of hypothyroidism, with the exception of weight gain, are
resolved with treatment with thyroid hormone, it is less likely that the
weight gain is solely due to the thyroid. Once hypothyroidism has been
treated and thyroid hormone levels have returned to the normal range
on thyroid hormone, the ability to gain or lose weight is the same as in
individuals who do not have thyroid problems.
Can thyroid hormone be used to help me lose weight?
Thyroid hormones have been used as a weight loss tool in the past. Many
studies have shown that excess thyroid hormone treatment can help
produce more weight loss than can be achieved by dieting alone.
However, once the excess thyroid hormone is stopped, the excess weight
loss is usually regained. Furthermore, there may be significant negative
consequences from the use of thyroid hormone to help with weight
loss, such as the loss of muscle protein in addition to any loss of body
fat. Pushing the thyroid hormone dose to cause thyroid hormone levels
to be elevated is unlikely to significantly change weight and may result
in other metabolic problems.
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