Hyperthyroidism and Weight Loss

What is the relationship between hyperthyroidism and weight?

Since the BMR in patients with hyperthyroidism is elevated, many                                                               patients with an overactive thyroid do,

indeed, experience some weight loss. Furthermore, the likelihood of

weight loss occurring is related to the severity of the overactive thyroid.

Thus, if the thyroid is extremely overactive, the individual’s BMR

increases which leads to increased caloric requirements to maintain

that weight. If the person does not increase the calories consumed to

match the excess calories burned, then weight loss will ensue. As

indicated earlier, the factors that control our appetite, metabolism, and

activity are very complex and thyroid hormone is only one factor in

this complex system. Nevertheless, on average the more severe the

hyperthyroidism, the greater the weight loss observed. Weight loss is

also observed in other conditions where thyroid hormones are elevated,

                                                                                                                                                                       such as in the toxic phase of thyroiditis  and

if one is on too high a dose of thyroid hormone pills. Since

hyperthyroidism also increases appetite, some patients may not lose

weight, and some may actually gain weight, depending on how much

they increase their caloric intake.

Why do I gain weight when hyperthyroidism is treated?

Because the hyperthyroidism is an abnormal state, we can predict that

any weight loss caused by the abnormal state would not be maintained

when the abnormal state is reversed. This is indeed what we find. On

the average, any weight lost during the hyperthyroid state is regained

when the hyperthyroidism is treated. One consequence of this

observation is that the use of thyroid hormone to treat obesity is not

very useful. Once thyroid hormone treatment is stopped, any weight that

is lost while on treatment will be regained after treatment is

discontinued.

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